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Test Directory

Hydrocodone and Metabolite, Serum

Test Summary

Therapeutic drug monitoring and confirmation of screen- positive results. Hydrocodone is an active component of Vicodin®, Lorcet®, Lortab®, etc. Serum half-life is 3.4 to 8.8 hours. Hydromorphone is an active ingredient in Dilaudid®. Serum half-life is 1.5 to 3.8 hours.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL serum collected in a red-top (no gel)

Minimum Volume

2.5 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 14 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum Separator Tubes (SST®)

Order Code

HYCDSR

EPIC (Premier) Code

LAB5873

Includes

Hydrocodone, Free and Hydromorphone, Free

CPT Code

  • 80361

Billing Code

  • 670077

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia CA, 91355

Department

Reference Testing

Reference Range

Hydrocodone, Free 5.0-24.0 ng/mL
Hydromorphone, Free 5.0-30.0 ng/mL

Setup Schedule / Expected Turnaround Time

Tuesday, Saturday morning; Report available: 2 - 5 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL serum collected in a red-top (no gel)

Minimum Volume

2.5 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 14 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum Separator Tubes (SST®)

Billing

CPT Code

  • 80361

Billing Code

  • 670077

CPT Statement

Result Information

Methodology

Chromatography/Mass Spectrometry

Testing Laboratory

N/A

Reference Range

Hydrocodone, Free 5.0-24.0 ng/mL
Hydromorphone, Free 5.0-30.0 ng/mL

Setup Schedule / Expected Turnaround Time

Tuesday, Saturday morning; Report available: 2 - 5 days