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Zinc Protoporphyrin (ZPP)

Test Summary

Zinc protoporphyrin (ZPP) accumulates in erythrocytes as a result of chronic lead absorption or iron deficiency anemia.

Aliases

  • Protoporphyrin Zinc, Zinc Protoporphyrin, ZPP

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL (0.5 mL minimum; pediatric 0.2 mL minimum) whole blood
collected in an EDTA (tan-top) tube

 

Minimum Volume

0.5 mL • Pediatric specimen: 0.2 mL

Instructions

Use a lead-free tube if a blood lead is also requested. 

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 10 days
  • Frozen: Unacceptable

Limitations

Aluminum and anemia of chronic disease may cause elevated results.

Other Acceptable Specimens

Whole blood collected in: EDTA (royal blue-top) tube, sodium heparin (royal blue-top) tube, sodium or lithium heparin (green-top) tube

Unacceptable Specimens

EDTA lavender top, Hemolysis, Received frozen, Clotted

Order Code

ZPP

EPIC (Premier) Code

LAB3489

Includes

N/A

CPT Code

  • 84202

Billing Code

  • 700000

CPT Statement

Methodology

Hematofluorometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Reference Range

Industrial Exposure <100 mcg/dL
(Refer to current OSHA regulation for exposure criteria.)

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 1 - 2 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL (0.5 mL minimum; pediatric 0.2 mL minimum) whole blood
collected in an EDTA (tan-top) tube

 

Minimum Volume

0.5 mL • Pediatric specimen: 0.2 mL

Instructions

Use a lead-free tube if a blood lead is also requested. 

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 10 days
  • Frozen: Unacceptable

Limitations

Aluminum and anemia of chronic disease may cause elevated results.

Other Acceptable Specimens

Whole blood collected in: EDTA (royal blue-top) tube, sodium heparin (royal blue-top) tube, sodium or lithium heparin (green-top) tube

Unacceptable Specimens

EDTA lavender top, Hemolysis, Received frozen, Clotted

Billing

CPT Code

  • 84202

Billing Code

  • 700000

CPT Statement

Result Information

Methodology

Hematofluorometry

Testing Laboratory

N/A

Reference Range

Industrial Exposure <100 mcg/dL
(Refer to current OSHA regulation for exposure criteria.)

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 1 - 2 days