von Willebrand Antigen, Multimeric Analysis
Test Summary
von Willebrand Disease is the most common hereditary bleeding disorder and it may also be acquired. Von Willebrand Factor (VWF) is critical for normal hemostasis; mediating platelet adhesion to the damaged endothelium and protecting Factor VIII from proteolytic degradation in circulation. VWF Multimeric Analysis is used to assist in categorizing disease subtype.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.2 mL
Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
VWFMLT
EPIC (Premier) Code
LAB3555
Includes
N/A
CPT Code
- 85247
Billing Code
- 671043
CPT Statement
Methodology
Electrophoresis
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
Normal
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 4 - 8 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.2 mL
Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Electrophoresis
Testing Laboratory
N/A
Reference Range
Normal
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 4 - 8 days