Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers
Test Summary
Antigen specific IgG and IgM titers allow rapid diagnosis of infection by one or more of the typhus fever group of rickettsial agents. This group includes Rickettsia typhi (endemic or murine typhus) R. prowazekii (epidemic typhus), and Brill-Zinsser disease caused by reactivation of latent R. prowazekii.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 day
Limitations
Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic
Order Code
TYPHUS
EPIC (Premier) Code
LAB3892
Includes
If R. typhi IgG is Detected, then R. typhi IgG Titer will be performed at an additional charge (CPT code(s): 86757).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86757).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86757).
CPT Code
- 86757 (x2)
Billing Code
- 700000
CPT Statement
Methodology
Immunofluorescence Assay (IFA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Reference Range
| Screen | Titer | |||||
| R. typhi IgG | Not detected | <1:64 | ||||
| R. typhi IgM | Not detected | <1:64 | ||||
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 1 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 day
Limitations
Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic
Result Information
Methodology
Immunofluorescence Assay (IFA)
Testing Laboratory
N/A
Reference Range
| Screen | Titer | |||||
| R. typhi IgG | Not detected | <1:64 | ||||
| R. typhi IgM | Not detected | <1:64 | ||||
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 1 - 4 days