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Drug Monitor, Tapentadol, Quanitative, Urine

Test Summary

Tapentadol is approved for the treatment of moderate to severe acute pain. Due to its dual mechanism of action as an opioid agonist and norepinephrine reuptake inhibitor, there is potential for ON LABEL for chronic pain. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of tapentadol is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL urine collected in a clinical drug test transport vial

Minimum Volume

2 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 7 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Urine collected in urine collection container

Unacceptable Specimens

Preserved samples

Order Code

TPENMM

EPIC (Premier) Code

LAB6635

Includes

N/A

CPT Code

  • 80372

Billing Code

  • 671291

CPT Statement

Methodology

Mass Spectrometry (MS)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

N/A

Setup Schedule / Expected Turnaround Time

Daily; Report available: 3 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL urine collected in a clinical drug test transport vial

Minimum Volume

2 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 7 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Urine collected in urine collection container

Unacceptable Specimens

Preserved samples

Billing

CPT Code

  • 80372

Billing Code

  • 671291

CPT Statement

Result Information

Methodology

Mass Spectrometry (MS)

Testing Laboratory

N/A

Reference Range

N/A

Setup Schedule / Expected Turnaround Time

Daily; Report available: 3 days