Thyroid Cancer (Thyroglobulin) Monitoring
Order Code: THYMON
Test Summary
Thyroglobulin measurements are most useful in the postoperative monitoring of patients with papillary, follicular, and Hurthle cell carcinomas. However, approximately 20% of individuals develop autoantibodies to thyroglobulin. Since these antibodies interfere with immunoassay measurement of thyroglobulin, it is necessary to determine the presence or absence of antibodies before measuring thyroglobulin. This panel provides a sensitive method for determination of thyroglobulin autoantibodies, with subsequent measurement of thyroglobulin by either a sensitive immunoassay (Tg Ab negative samples) or LCMSMS (Tg Ab positive samples). The mass spectrometry assay has no interference from autoantibodies.
Aliases
- Thyroglobulin (Tg)
- Thyroglobulin Tumor Markers
- Thyroglobulin Antibody
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL serum
Minimum Volume
1.5 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated
Specimen Stability
- Room temperature: 6 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Lipemia • Plasma • Icteric
Order Code
THYMON
EPIC (Premier) Code
LAB5385
Includes
N/A
CPT Code
- 86800
Billing Code
- 670717
CPT Statement
Methodology
Immunoassay • Liquid Chromatography/Tandem Mass Spectrometry
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
≤2 IU/mL
Setup Schedule / Expected Turnaround Time
Tuesday - Sunday; Report available: 7 - 8 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL serum
Minimum Volume
1.5 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated
Specimen Stability
- Room temperature: 6 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Lipemia • Plasma • Icteric
Result Information
Methodology
Immunoassay • Liquid Chromatography/Tandem Mass Spectrometry
Testing Laboratory
N/A
Reference Range
≤2 IU/mL
Setup Schedule / Expected Turnaround Time
Tuesday - Sunday; Report available: 7 - 8 days