Thyroglobulin Panel
Test Summary
Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis.
Deficient TG synthesis is observed in infants with goitrous hypo-thyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. With immunometric assays (sandwich assays), TGAB interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent antibodies from binding endogenous TG.
Aliases
- Quantitative Thyrogloblin, Thyrogloblin, Thyrogloblin Evaluation, Thyrogloblin Level, Thyrogloblin,Quantitative
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic
Order Code
THG
EPIC (Premier) Code
LAB384
Includes
Thyroglobulin Antibodies and Quantitative Thyroglobulin
CPT Code
- 84432
- 86800
Billing Code
- 670712
- 670713
CPT Statement
Methodology
Immunoassay (IA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 1 - 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Instructions
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic
Result Information
Methodology
Immunoassay (IA)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 1 - 3 days