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Test Directory

Plasma Renin Activity, LC/MS/MS

Test Summary

Measurement of the Plasma Renin activity is useful in evaluating hypertension.

Aliases

  • PRA

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.8 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Instructions

Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 24 hours
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Plasma separator tube • Gross hemolysis • Grossly lipemic • Thawed specimen

Order Code

RENIN

EPIC (Premier) Code

LAB4295

Includes

N/A

CPT Code

  • 84244

Billing Code

  • 670452

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

0.25-5.82 ng/mL/h

Setup Schedule / Expected Turnaround Time

Daily; Report available: 4 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.8 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Instructions

Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 24 hours
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Plasma separator tube • Gross hemolysis • Grossly lipemic • Thawed specimen

Billing

CPT Code

  • 84244

Billing Code

  • 670452

CPT Statement

Result Information

Methodology

Chromatography/Mass Spectrometry

Testing Laboratory

N/A

Reference Range

0.25-5.82 ng/mL/h

Setup Schedule / Expected Turnaround Time

Daily; Report available: 4 days