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Rickettsia Antibody Panel with Reflex to Titers

Test Summary

Antigen-specific IgG and IgM titers allow rapid diagnosis of infection by organisms within either of the two major groups of Rickettsia. The spotted fever group includes R. rickettsia (Rocky Mountain Spotted Fever) and R. akari (Rickettsial pox). The typhus group includes R. typhi (endemic/murine typhus) and R. prowazekii (epidemic typhus).

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days

Limitations

Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic

Order Code

RCKAB

EPIC (Premier) Code

LAB3893

Includes

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers
Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

If Rickettsia (RMSF) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).
If Rickettsia (Typhus Fever) screen is Detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s) 86757 per titer performed).

CPT Code

  • 86757 (x4)

Billing Code

  • 670457
  • 670749

CPT Statement

Methodology

Immunofluorescence Assay (IFA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Reference Range

Screen Titer
RMSF IgG Not detected <1:64
RMSF IgM Not detected <1:64
R. typhi IgG Not detected <1:64
R. typhi IgM Not detected <1:64

Setup Schedule / Expected Turnaround Time

Tuesday - Saturday; Report available: 1 - 4 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days

Limitations

Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic

Billing

CPT Code

  • 86757 (x4)

Billing Code

  • 670457
  • 670749

CPT Statement

Result Information

Methodology

Immunofluorescence Assay (IFA)

Testing Laboratory

N/A

Reference Range

Screen Titer
RMSF IgG Not detected <1:64
RMSF IgM Not detected <1:64
R. typhi IgG Not detected <1:64
R. typhi IgM Not detected <1:64

Setup Schedule / Expected Turnaround Time

Tuesday - Saturday; Report available: 1 - 4 days