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Test Directory

Pyruvic Acid (Pyruvate), Blood

Test Summary

Increased pyruvic acid levels have been associated with diabetes mellitus, vitamin deficiencies, uremia, congestive heart failure, liver diseases, muscular dystrophy, thiamine deficiency, and neoplastic conditions. Pyruvic acid is useful in assessing oxygen deprivation and provides an index of the severity of circulatory failure.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

4.5 mL protein-free filtrate in a plastic leak-proof aliquot tube (see instructions)

Minimum Volume

2 mL

Instructions

Collect 4 mL whole blood EDTA (lavender-top), sodium or lithium heparin (green-top), or fluoride oxalate (gray-top) tube and immediately, vigorously mix with 4 mL pre-chilled, ice cold 7% or 8% Perchloric Acid.
Let mixture stand for 10 minutes; then, centrifuge. Separate and submit 4.5 mL supernatant fluid for assay, refrigerated 2-8°C. Transport refrigerated (cold packs). Maintain 1:1 ratio for whole blood and Perchloric acid.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: 30 days
  • Frozen: 90 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Order Code

PYRUV

EPIC (Premier) Code

LAB969

Includes

N/A

CPT Code

  • 84210

Billing Code

  • 670447

CPT Statement

Methodology

Enzymatic

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

0.30-1.50 mg/dL

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 1-3 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

4.5 mL protein-free filtrate in a plastic leak-proof aliquot tube (see instructions)

Minimum Volume

2 mL

Instructions

Collect 4 mL whole blood EDTA (lavender-top), sodium or lithium heparin (green-top), or fluoride oxalate (gray-top) tube and immediately, vigorously mix with 4 mL pre-chilled, ice cold 7% or 8% Perchloric Acid.
Let mixture stand for 10 minutes; then, centrifuge. Separate and submit 4.5 mL supernatant fluid for assay, refrigerated 2-8°C. Transport refrigerated (cold packs). Maintain 1:1 ratio for whole blood and Perchloric acid.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: 30 days
  • Frozen: 90 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Billing

CPT Code

  • 84210

Billing Code

  • 670447

CPT Statement

Result Information

Methodology

Enzymatic

Testing Laboratory

N/A

Reference Range

0.30-1.50 mg/dL

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 1-3 days