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Protein Total and Protein Electrophoresis, CSF

Test Summary

To evaluate protein composition of cerebrospinal fluid and may be useful in neurological diseases or tumors in central nervous system. This assay is not recommended for the assessment of multiple sclerosis for which oligoclonal bands in CSF and serum should be ordered.

Aliases

  • PEP (CSF)

Specimen Collection

Special Instructions

N/A

Preferred Specimen

6 mL CSF collected in a sterile, leak-proof CSF container

Minimum Volume

3.5 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis

Order Code

PECSF

EPIC (Premier) Code

LAB346

Includes

Protein, Total, CSF
Protein Electrophoresis, CSF

CPT Code

  • 84157
  • 84166

Billing Code

  • 670413
  • 670414

CPT Statement

Methodology

Agarose Gel Electrophoresis • Spectrophotometry (SP)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

Protein, Total, CSF
  <1 month 15-100 mg/dL
  1 month-60 years 15-45 mg/dL
  >60 years 15-60 mg/dL
Prealbumin  1.3-6.9 %
Albumin 51.9-67.8 %
Alpha-1-Globulin  1.8-6.5 %
Alpha-2-Globulin 4.6-10.8 %
Beta Globulin 7.8-18.2 %
Gamma Globulin 4.8-17.6 %

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 3 - 5 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

6 mL CSF collected in a sterile, leak-proof CSF container

Minimum Volume

3.5 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis

Billing

CPT Code

  • 84157
  • 84166

Billing Code

  • 670413
  • 670414

CPT Statement

Result Information

Methodology

Agarose Gel Electrophoresis • Spectrophotometry (SP)

Testing Laboratory

N/A

Reference Range

Protein, Total, CSF
  <1 month 15-100 mg/dL
  1 month-60 years 15-45 mg/dL
  >60 years 15-60 mg/dL
Prealbumin  1.3-6.9 %
Albumin 51.9-67.8 %
Alpha-1-Globulin  1.8-6.5 %
Alpha-2-Globulin 4.6-10.8 %
Beta Globulin 7.8-18.2 %
Gamma Globulin 4.8-17.6 %

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 3 - 5 days