Osteocalcin, N-MID
Test Summary
Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, e.g., osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease.
Aliases
- N/A
Specimen Collection
Special Instructions
Patient Preparation: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 24 hours
- Frozen 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Heat inactivated specimens • Specimens stabilized with azide • Patient administered with biotin within 8 hours
Order Code
OSTEOC
EPIC (Premier) Code
LAB5899
Includes
N/A
CPT Code
- 83937
Billing Code
- 670372
CPT Statement
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
| Male (ng/mL) | Female (ng/mL) | |
| 0-4 Years | Not established | Not established |
| 5-9 Years | 47-142 | 47-142 |
| 10-13 Years | 49-167 | 49-167 |
| 14-17 Years | 26-203 | 14-85 |
| >17 Years | 9-38 | 8-32 |
Setup Schedule / Expected Turnaround Time
Monday - Saturday morning; Report available: Next day
Specimen Collection
Special Instructions
Patient Preparation: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 24 hours
- Frozen 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Heat inactivated specimens • Specimens stabilized with azide • Patient administered with biotin within 8 hours
Result Information
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
Testing Laboratory
N/A
Reference Range
| Male (ng/mL) | Female (ng/mL) | |
| 0-4 Years | Not established | Not established |
| 5-9 Years | 47-142 | 47-142 |
| 10-13 Years | 49-167 | 49-167 |
| 14-17 Years | 26-203 | 14-85 |
| >17 Years | 9-38 | 8-32 |
Setup Schedule / Expected Turnaround Time
Monday - Saturday morning; Report available: Next day