Oligoclonal Bands (IgG), CSF
Order Code:
OLIGO
Test Summary
Oligoclonal bands are present in the CSF of more than 85% of patients with clinically definite multiple sclerosis (MS). To distinguish between oligoclonal bands in the CSF due to a peripheral gammopathy and oligoclonal bands due to local production in the CNS, serum and CSF should be tested simultaneously. Oligoclonal bands can however be observed in a variety of other diseases, e.g., subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, and brain tumors and infarctions.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL CSF collected in a sterile CSF collection tube #4 and 1 mL serum
Minimum Volume
0.5 mL
Instructions
Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 8 hours
- Refrigerated: 20 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature
Order Code
OLIGO
EPIC (Premier) Code
LAB10086
Includes
N/A
CPT Code
- 83916
Billing Code
- 670362
CPT Statement
Methodology
Isoelectric Focusing (IEF)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
Absent
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 4 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL CSF collected in a sterile CSF collection tube #4 and 1 mL serum
Minimum Volume
0.5 mL
Instructions
Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 8 hours
- Refrigerated: 20 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature
Result Information
Methodology
Isoelectric Focusing (IEF)
Testing Laboratory
N/A
Reference Range
Absent
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 4 - 6 days