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Mitochondrial Antibody Screen with Reflex to Titer

Test Summary

A high Anti-Mitochondrial Antibody (AMA) titer supports the diagnosis of primary biliary cirrhosis (PBC). Low titers of AMA may be detected in other liver disorders, which include chronic active hepatitis and cryptogenic cirrhosis. Mitochondrial M2 Antibody has an even higher specificity for PBC.

Aliases

  • Anti Mitochondrial Antibody

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.5 mL serum

Minimum Volume

0.1 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic

Order Code

MITOC

EPIC (Premier) Code

LAB048

Includes

If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).

CPT Code

  • 86381

Billing Code

  • 670331

CPT Statement

Methodology

Immunofluorescence Assay (IFA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

Negative

Setup Schedule / Expected Turnaround Time

Monday - Friday; Report available: Next day

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.5 mL serum

Minimum Volume

0.1 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic

Billing

CPT Code

  • 86381

Billing Code

  • 670331

CPT Statement

Result Information

Methodology

Immunofluorescence Assay (IFA)

Testing Laboratory

N/A

Reference Range

Negative

Setup Schedule / Expected Turnaround Time

Monday - Friday; Report available: Next day