Metanephrines, Fractionated, LCMSMS, Random Urine
Test Summary
Useful in the evaluation of pheochromocytoma.
Aliases
- Metanephrine / Creatinine Ratio
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL random urine(1.5 mL minimum)
Minimum Volume
1.5 mL
Instructions
After urine collection, add 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Record patients age on test request form and urine vial.
Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.
Storage
N/A
Transport Temperature
Preserved urine: Room temperature
Unpreserved urine: Frozen
Unpreserved urine: Frozen
Specimen Stability
- Preserved urine
- Room temperature: 10 days
- Refrigerated: 14 days
- Frozen: 90 days
- Unpreserved urine
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Unpreserved random urine
Unacceptable Specimens
Urine collected with boric acid
Order Code
METFRU
EPIC (Premier) Code
LAB3197
Includes
Metanephrines, Normetanephrines, Total Metanephrines, Creatinine
CPT Code
- 82570
- 83835
Billing Code
- 670172
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL random urine(1.5 mL minimum)
Minimum Volume
1.5 mL
Instructions
After urine collection, add 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Record patients age on test request form and urine vial.
Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.
Storage
N/A
Transport Temperature
Preserved urine: Room temperature
Unpreserved urine: Frozen
Unpreserved urine: Frozen
Specimen Stability
- Preserved urine
- Room temperature: 10 days
- Refrigerated: 14 days
- Frozen: 90 days
- Unpreserved urine
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Unpreserved random urine
Unacceptable Specimens
Urine collected with boric acid
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 - 4 days