JC Polyoma Virus DNA, Qualitative Real-Time PCR, Serum or Plasma
Test Summary
JC polyoma virus is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC polyoma virus DNA in CSF, urine or plasma. Detection of virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JVC can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.7 mL plasma collected in an EDTA (lavender-top) tube, or EDTA PPT (white-top) tube
Minimum Volume
0.3 mL plasma • 0.3 mL serum
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 48 hours
- Refrigerated: 7 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Plasma collected in: ACD solution A (yellow-top) tube • 0.7 mL Serum
Unacceptable Specimens
N/A
Order Code
JCPOLY
EPIC (Premier) Code
LAB3273
Includes
N/A
CPT Code
- 87798
Billing Code
- 700000
CPT Statement
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Reference Range
Not detected
Setup Schedule / Expected Turnaround Time
Daily; Report available: 1 day
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.7 mL plasma collected in an EDTA (lavender-top) tube, or EDTA PPT (white-top) tube
Minimum Volume
0.3 mL plasma • 0.3 mL serum
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 48 hours
- Refrigerated: 7 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Plasma collected in: ACD solution A (yellow-top) tube • 0.7 mL Serum
Unacceptable Specimens
N/A
Result Information
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
Testing Laboratory
N/A
Reference Range
Not detected
Setup Schedule / Expected Turnaround Time
Daily; Report available: 1 day