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Test Directory JC Polyoma Virus DNA, Qualitative Real-Time PCR, CSF

JC Polyoma Virus DNA, Qualitative Real-Time PCR, CSF

Test Summary

JC Polyoma Virus (JCV) is the cause of progressive multi- focal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC polyoma virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.7 mL CSF collected in a sterile, leak-proof container

Minimum Volume

0.3 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Frozen

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Order Code

JCPLY

EPIC (Premier) Code

LAB5925

Includes

N/A

CPT Code

87798

Billing Code

700000

CPT Statement

Methodology

Real-Time Polymerase Chain Reaction (RT-PCR)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Reference Range

Not detected

Setup Schedule / Expected Turnaround Time

Daily; Report available: 1 day