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Test Directory

Test Directory Imipramine

Imipramine

Test Summary

Imipramine is a tricyclic antidepressant drug used to treat depression. Therapeutic drug monitoring is used to optimize dose and to avoid toxicity.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL serum collected in a red-top tube (no gel)

Minimum Volume

1.5 mL

Instructions

Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.

Patient Preparation

N/A

Storage

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 5 days
Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube

Unacceptable Specimens

Gross hemolysis • Gel barrier/Serum separator tube (SST)

Order Code

IMIPRM

EPIC (Premier) Code

LAB259

Includes

Imipramine, Desipramine and Total

CPT Code

80299

Billing Code

670101

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

Total

150-250 mcg/L

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 1 - 2 days