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IgG Synthesis Rate/Index, CSF

Test Summary

The IgG Synthesis Rate/Index is useful in diagnosing and monitoring patients with multiple sclerosis and other inflammatory diseases involving the brain and meninges.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL CSF and 1 mL serum

Minimum Volume

1 mL CSF and 0.5 mL serum

Instructions

Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.

CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.

Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 8 hours
  • Refrigerated: 7 days
  • Frozen: 90 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Received room temperature • Xanthochromia; RBCs • Hemolysis in CSF

Order Code

IGGIDX

EPIC (Premier) Code

LAB257

Includes

Albumin (CSF and Serum)
IgG (CSF and Serum)
IgG Index, CSF
Synthesis Rate IgG, CSF

CPT Code

  • 82040
  • 82042
  • 82784 (x2)

Billing Code

  • 670091
  • 670092
  • 670093

CPT Statement

Methodology

Nephelometry

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 2 - 5 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL CSF and 1 mL serum

Minimum Volume

1 mL CSF and 0.5 mL serum

Instructions

Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.

CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.

Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 8 hours
  • Refrigerated: 7 days
  • Frozen: 90 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Received room temperature • Xanthochromia; RBCs • Hemolysis in CSF

Billing

CPT Code

  • 82040
  • 82042
  • 82784 (x2)

Billing Code

  • 670091
  • 670092
  • 670093

CPT Statement

Result Information

Methodology

Nephelometry

Testing Laboratory

N/A

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 2 - 5 days