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Inflammatory Bowel Disease Differentiation Panel

Test Summary

This panel is useful in the diagnosis of  Inflammatory Bowel diseases and can help to distinguish patients with ulcerative colitis from those with Crohn's Disease.

Aliases

  • IBD Differentiation Panel

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL serum

Minimum Volume

1.4 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 21 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly icteric • Lipemic

Order Code

IBD

EPIC (Premier) Code

LAB4490

Includes

ANCA Screen with Reflex to ANCA Titer
Myeloperoxidase Antibody (MPO)
Proteinase-3 Antibody
Saccharomyces cerevisiae Antibodies (ASCA) (IgG)
Saccharomyces cerevisiae Antibodies (ASCA) (IgA)

If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86021 for each titer performed).

CPT Code

  • 86021 (x2)
  • 86036
  • 86671 (x2)

Billing Code

  • 670567
  • 670463
  • 670442
  • 670342
  • 670555

CPT Statement

Methodology

Immunoassay (IA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

ANCA Screen Negative
  P-ANCA Titer <1:20
  C-ANCA Titer <1:20
  Atypical P-ANCA Titer <1:20

Myeloperoxidase Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Proteinase-3 Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Saccharomyces cerevisiae Ab (IgG)
≤20.0 U Negative
20.1-29.9 U Equivocal
≥30.0 U Positive

Saccharomyces cerevisiae Ab (IgA)
≤20.0 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 3 - 5 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

2 mL serum

Minimum Volume

1.4 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 21 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly icteric • Lipemic

Billing

CPT Code

  • 86021 (x2)
  • 86036
  • 86671 (x2)

Billing Code

  • 670567
  • 670463
  • 670442
  • 670342
  • 670555

CPT Statement

Result Information

Methodology

Immunoassay (IA)

Testing Laboratory

N/A

Reference Range

ANCA Screen Negative
  P-ANCA Titer <1:20
  C-ANCA Titer <1:20
  Atypical P-ANCA Titer <1:20

Myeloperoxidase Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Proteinase-3 Antibody
<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Saccharomyces cerevisiae Ab (IgG)
≤20.0 U Negative
20.1-29.9 U Equivocal
≥30.0 U Positive

Saccharomyces cerevisiae Ab (IgA)
≤20.0 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 3 - 5 days