Histoplasma Antibody, Complement Fixation, Serum
Test Summary
This test is used for the diagnosis and prognosis of histoplasma infections. Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Please note: For CSF use test code 5297 or 5297X Histoplasma Antibody, Complement Fixation, CSF
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Grossly icteric
Order Code
HISTCF
EPIC (Premier) Code
LAB3486
Includes
Yeast Phase Antibody and Mycelial Phase Antibody
CPT Code
- 86698 (x2)
Billing Code
- 670046
CPT Statement
Methodology
Complement Fixation (CF)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
| Yeast Phase Ab | <1:8 titer |
| Mycelial Phase Ab | <1:8 titer |
Interpretive Criteria
| <1:8 | Antibody Not Detected |
| ≥1:8 | Antibody Detected |
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday morning; Report available: 2 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Please note: For CSF use test code 5297 or 5297X Histoplasma Antibody, Complement Fixation, CSF
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Grossly icteric
Result Information
Methodology
Complement Fixation (CF)
Testing Laboratory
N/A
Reference Range
| Yeast Phase Ab | <1:8 titer |
| Mycelial Phase Ab | <1:8 titer |
Interpretive Criteria
| <1:8 | Antibody Not Detected |
| ≥1:8 | Antibody Detected |
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday morning; Report available: 2 days