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Gabapentin

Test Summary

Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.

Aliases

  • Neurotin

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.5 mL

Instructions

Separate serum or plasma from red cells as soon as possible; Pipette or pour into plastic transport tubes.

Patient Preparation

Draw sample 2 hours after last dose

Storage

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 12 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube

Unacceptable Specimens

Gel barrier/Serum Separator Tube (SST®) • Gross hemolysis

Order Code

GABAP

EPIC (Premier) Code

LAB211

Includes

N/A

CPT Code

  • 80171

Billing Code

  • 700000

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Reference Range

2.7-4.1: (peak) following a single dose of 900-1800 mg/day.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.

The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.

Setup Schedule / Expected Turnaround Time

Monday - Saturday morning; Report available: Next day

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.5 mL

Instructions

Separate serum or plasma from red cells as soon as possible; Pipette or pour into plastic transport tubes.

Patient Preparation

Draw sample 2 hours after last dose

Storage

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 12 days
  • Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube

Unacceptable Specimens

Gel barrier/Serum Separator Tube (SST®) • Gross hemolysis

Billing

CPT Code

  • 80171

Billing Code

  • 700000

CPT Statement

Result Information

Methodology

Chromatography/Mass Spectrometry

Testing Laboratory

N/A

Reference Range

2.7-4.1: (peak) following a single dose of 900-1800 mg/day.
4.0-8.5: (peak) following a multiple dose of 900-1800 mg/day administration.

The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL.

Setup Schedule / Expected Turnaround Time

Monday - Saturday morning; Report available: Next day