FISH, Follicular Lymphoma, IGH/BCL2, t(14;18)
Order Code:
FOLLIC
Test Summary
Translocation t(14;18)(q32;q21.3) is assayed by FISH with probes from the regions IGH (14q32) and BCL2 (18q21.3) this assay is useful to diagnose follicular lymphoma (>75%) and diffuse large cell lymphomas (25%).
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top), sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube,or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL whole blood or bone marrow • 5x5 mm tissue
Instructions
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: See instructions
- Refrigerated: See instructions
- Frozen: See instructions
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
FOLLIC
EPIC (Premier) Code
LAB3279
Includes
Note: If results are not possible, the test order may be canceled and replaced by a "Cytogenetics Communication".
CPT Code
- 88275
- 88271 (x2)
Billing Code
- 670936
- 670937
CPT Statement
Methodology
Fluorescence In Situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Mornings
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top), sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube,or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL whole blood or bone marrow • 5x5 mm tissue
Instructions
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: See instructions
- Refrigerated: See instructions
- Frozen: See instructions
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Fluorescence In Situ Hybridization (FISH)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Mornings