Fibrin Monomer
Test Summary
The Fibrin monomer assay is a qualitative test for the detection of soluble fibrin monomers in plasma. Fibrin monomers are an intermediate product of thrombin proteolysis of fibrinogen. With disseminated intravascular coagulation (DIC) there is an excess of thrombin generation and therefore detectable levels of soluble fibrin monomer. This test may be used in combination with other markers (platelet count, fibrinogen level, D-dimer) and the clinical scenario to determine the presence of DIC.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Order Code
FIBRMN
EPIC (Premier) Code
LAB6173
Includes
N/A
CPT Code
- 85362
Billing Code
- 670997
CPT Statement
Methodology
Hemagglutination (HA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
Negative
Setup Schedule / Expected Turnaround Time
Monday Night Report available: 1 day
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Result Information
Methodology
Hemagglutination (HA)
Testing Laboratory
N/A
Reference Range
Negative
Setup Schedule / Expected Turnaround Time
Monday Night Report available: 1 day