Carbamazepine-10,11-Epoxide, Serum/Plasma
Test Summary
Carbamazepine and its metabolite (10,11-Carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein bound states.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s).
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 14 days
- Frozen: 10 months
Limitations
N/A
Other Acceptable Specimens
Plasma collected in an EDTA (lavender-top) tube
Unacceptable Specimens
Serum separator tube (SST®)
Order Code
CRBMET
EPIC (Premier) Code
LAB3865
Includes
N/A
CPT Code
- 80161
Billing Code
- 670235
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
0.2-2.0 mcg/mL
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s).
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 14 days
- Frozen: 10 months
Limitations
N/A
Other Acceptable Specimens
Plasma collected in an EDTA (lavender-top) tube
Unacceptable Specimens
Serum separator tube (SST®)
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
0.2-2.0 mcg/mL
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 days