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Test Directory Complement, Total (CH50)

Complement, Total (CH50)

Test Summary

CH50 is a screening test for total complement activity. Levels of complement may be depressed in genetic deficiency, liver disease, chronic glomerulonephritis, rheumatoid arthritis, hemolytic anemias, graft rejection, systemic lupus erythematosis, acute glomerulonephritis, subacute bacterial endocarditis and cryoglobulinemia. Elevated complement may be found in acute inflammatory conditions, leukemia, Hodgkin's Disease, sarcoma, and Behcet's Disease.

Aliases

Total Complement CH50 CH-50 Hemolytic Complement

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Avoid hemolysis. Centrifuge serum specimens within 1 hour of collection. Immediately pipette serum into "sterile, plastic, screw-capped vial(s) and freeze solid" at -20°C or lower. Do not allow samples to thaw. With multiple tests, submit a separate tube for each test. Send frozen samples on dry ice to the laboratory. Do not submit the sample in a glass tube.

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 7 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Lipemia • Received thawed

Order Code

CH50

EPIC (Premier) Code

LAB115

Includes

N/A

CPT Code

86162

Billing Code

670176

CPT Statement

Methodology

Liposome

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

31-60 U/mL

Setup Schedule / Expected Turnaround Time

Monday - Saturday morning; Report available: Next day