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Test Directory Coccidioides Antibody, Complement Fixation, Serum

Coccidioides Antibody, Complement Fixation, Serum

Test Summary

Infection by Coccidioides immitis can produce a spectrum of disease, with most patients being asymptomatic and some developing disseminated disease, including pneumonia and meningitis.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Instructions

For CSF, use test code 5295X Coccidioides Antibody, Complement Fixation, CSF.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Limitations

False-negatives may occur in patients with solitary pulmonary lesions. Patients with active histoplasmosis may generate cross reactions. Elevated serum antibodies may be present in patients with meningeal coccidiocomycosis.

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic • Grossly icteric

Order Code

CCIDAB

EPIC (Premier) Code

LAB5996

Includes

N/A

CPT Code

86635

Billing Code

670634

CPT Statement

Methodology

Complement Fixation (CF)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

<1:2 titer

Interpretive Criteria

<1:2	Antibody Not Detected
≥1:2	Antibody Detected

Setup Schedule / Expected Turnaround Time

Tuesday - Saturday; Report available: 2 - 5 days