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Test Directory

Test Directory Bupropion and Metabolite, Serum/Plasma

Bupropion and Metabolite, Serum/Plasma

Test Summary

Bupropion is an antidepressant for treating mental depression. Monitoring its level is important to optimize therapy, to avoid toxicity and to assure compliance.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL frozen serum collected in a red-top tube (no gel)

Minimum Volume

0.4 mL

Instructions

Collect as trough prior to next dose. Collect serum and remove from cells

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Limitations

N/A

Other Acceptable Specimens

Frozen plasma collected in: EDTA (lavender-top) tube

Unacceptable Specimens

Received room temperature • Received refrigerated • Gel barrier/Serum Separator Tube (SST®)

Order Code

BUPROP

EPIC (Premier) Code

LAB3676

Includes

Bupropion and Hydroxybupropion

CPT Code

80338 (HCPCS: G0480)

Billing Code

671178

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

Bupropion	50-100 ng/mL
Hydroxybupropion	600-2000 ng/mL

Setup Schedule / Expected Turnaround Time

Tuesday, Thursday, Saturday; Report available: 1 day