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Test Directory » FISH, B-cell Malignancy, IGH, 14q32 Rearrangement

Test Directory FISH, B-cell Malignancy, IGH, 14q32 Rearrangement

FISH, B-cell Malignancy, IGH, 14q32 Rearrangement

Order Code: BCELL

Test Summary

The splitting of IgH region of chromosome 14q32 is frequently implicated in translocations seen in a variety of hematological malignancies of B-cell origin.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top), sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube, or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue

Minimum Volume

1 mL whole blood or bone marrow • 5x5 tissue

Instructions

Clinical history and reason for referral are required with test order. Prior therapy and transplant history should be provided.
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.

Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

Room temperature: See instructions
Refrigerated: See instructions
Frozen: See instructions

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Order Code

BCELL

EPIC (Premier) Code

LAB6093

Includes

Note: If results are not possible, the test order may be canceled and replaced with a Cytogenetics Communication

CPT Code

88275
88271 (x2)

Billing Code

670934
670935

CPT Statement

Methodology

Fluorescence In Situ Hybridization (FISH)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Monday - Sunday evening; Report available: 5 days