Amylase Isoenzymes with Reflex to Macroamylase
Test Summary
Amylase is produced primarily in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Macroamylase is a laboratory and not a clinical entity. Amylase can complex with immunoglobulins or other high molecular weight proteins and serum amylase will appear falsely elevated. No clinical symptoms are associated with macroamylasemia.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature = Unacceptable
- Refrigerated = 7 days
- Frozen = 30 days
Limitations
Oxalate, citrate, and lipemic sera can decrease results.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Order Code
AMYISO
EPIC (Premier) Code
LAB3843
Includes
Amylase, Pancreatic Isoenzyme, Salivary Isoenzymes (calculated)
If Amylase Isoenzymes are >115 U/L, then Macroamylase will be performed at an additional charge (CPT code(s): 82150).
If Amylase Isoenzymes are >115 U/L, then Macroamylase will be performed at an additional charge (CPT code(s): 82150).
CPT Code
- 82150 (x2)
Billing Code
- 670553
CPT Statement
Methodology
Polyethylene Glycol Precipitation
Spectrophotometry
Spectrophotometry
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly VA, 20153
14225 Newbrook Drive
Chantilly VA, 20153
Department
Reference Testing
Reference Range
| Amylase | 21-101 U/L |
| Pancreatic Isoenzyme | 16-46 U/L |
| Salivary Isoenzymes | 4-61 U/L |
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 1 day
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature = Unacceptable
- Refrigerated = 7 days
- Frozen = 30 days
Limitations
Oxalate, citrate, and lipemic sera can decrease results.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Result Information
Methodology
Polyethylene Glycol Precipitation
Spectrophotometry
Spectrophotometry
Testing Laboratory
N/A
Reference Range
| Amylase | 21-101 U/L |
| Pancreatic Isoenzyme | 16-46 U/L |
| Salivary Isoenzymes | 4-61 U/L |
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 1 day