Posaconazole
Test Summary
The antifungal drug posaconazole is indicated for prophylaxis of invasive aspergillus and candida infections in severely immunocompromised patients. It may also be used in the treatment of oropharyngeal candidiasis refractory to itraconazole and fluconazole. The chronic nature of fungal infections demands constant monitoring of posaconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes (SST) • Other body fluids
Order Code
PZQZ
EPIC (Premier) Code
LAB6899
Includes
N/A
CPT Code
- 80187 - This test is not available for New York patient testing.
Billing Code
- 670841
CPT Statement
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Lewisville
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
Department
Reference Testing
Reference Range
after 7 days of treatment
| Target for prophylaxis purpose | trough level >0.7 mcg/mL |
| Target for salvage treatment | trough level >1.25 mcg/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 1 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes (SST) • Other body fluids
Billing
CPT Code
- 80187 - This test is not available for New York patient testing.
Billing Code
- 670841
CPT Statement
Result Information
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Testing Laboratory
N/A
Reference Range
after 7 days of treatment
| Target for prophylaxis purpose | trough level >0.7 mcg/mL |
| Target for salvage treatment | trough level >1.25 mcg/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 1 - 4 days