Itraconazole
Test Summary
The antifungal drug itraconazole is active in the treatment of aspergillosis, blastomycosis, histoplasmosis, sporotrichosis, and onychomycosis. It is a protein-bound drug and thus has negligible CSF penetration. It may also be utilized in the treatment of systemic candidiasis and cryptococcosis, especially when other drugs are contraindicated or ineffective. The chronic nature of fungal infections demands constant monitoring of itraconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes • Other body fluids
Order Code
ITRACZ
EPIC (Premier) Code
LAB5910
Includes
Itraconazole and OH-Itraconazole
CPT Code
- 80189 - This test is not available for New York patient testing.
Billing Code
- 670009
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Lewisville
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
Department
Reference Testing
Reference Range
| Itraconazole (trough) localized infection | >0.5 mcg/mL |
| Itraconazole (trough) systemic infection | >1.0 mcg/mL |
The total of Itraconazole and its active metabolite, hydroxyl-itraconazole, is 1-4 mcg/mL
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 1 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes • Other body fluids
Billing
CPT Code
- 80189 - This test is not available for New York patient testing.
Billing Code
- 670009
CPT Statement
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
| Itraconazole (trough) localized infection | >0.5 mcg/mL |
| Itraconazole (trough) systemic infection | >1.0 mcg/mL |
The total of Itraconazole and its active metabolite, hydroxyl-itraconazole, is 1-4 mcg/mL
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 1 - 4 days