Amoxicillin
Test Summary
The concentration of antimicrobial agents in body fluids, most notable serum or plasma, are used to regulate therapy to ensure effective dosing (especially with oral agents where GI absorption is in question), to monitor accumulation to help minimize toxicity, and to help evaluate the pharmacokinetics of new agents. Both peak and trough levels obtained immediately after dosing or immediately prior to new dosing, respectively, may be monitored.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Instructions
Specimens collected just before or within 15 minutes of the next antibiotic dose represent the trough level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes (SST) • Other body fluids
Order Code
AMOX
EPIC (Premier) Code
LAB6308
Includes
N/A
CPT Code
- 80299 - This test is not available for New York patient testing
Billing Code
- 670549
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Lewisville
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
2501 South State Highway 121
Suite 1100
Lewisville TX, 75067
Department
Reference Testing
Reference Range
| Therapeutic trough level | 0.5-1 mcg/mL |
| Therapeutic peak level | 5-15 mcg/mL |
Toxic range is not established. Interpretation of results should include clinical evaluation.
This assay tests amoxicillin alone since concentrations are equivalent for amoxicillin alone or amoxicillin clavulanate levels. This assay does not detect clavulanate levels.
Setup Schedule / Expected Turnaround Time
Wednesday, Saturday; Report available: 1 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Instructions
Specimens collected just before or within 15 minutes of the next antibiotic dose represent the trough level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level.
Specimens obtained within 15-30 minutes after the end of IV infusion, or 45-60 minutes after an IM injection, or 90 minutes after oral intake represent the peak level.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tubes (SST) • Other body fluids
Billing
CPT Code
- 80299 - This test is not available for New York patient testing
Billing Code
- 670549
CPT Statement
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
| Therapeutic trough level | 0.5-1 mcg/mL |
| Therapeutic peak level | 5-15 mcg/mL |
Toxic range is not established. Interpretation of results should include clinical evaluation.
This assay tests amoxicillin alone since concentrations are equivalent for amoxicillin alone or amoxicillin clavulanate levels. This assay does not detect clavulanate levels.
Setup Schedule / Expected Turnaround Time
Wednesday, Saturday; Report available: 1 - 5 days