Alpha Melanocyte Stimulating Hormone
Test Summary
Alpha MSH is a 13 amino acid peptide (1665 kD) with serine at the N terminal end and amidated valine at the C terminal end. Alpha MSH is derived from pro-opiomelanocorticotropin, a precursor protein which contains within its structure, the sequence of ACTH, beta MSH and gamma MSH. The amino acid sequence of alpha MSH is identical to ACTH 1-13 in humans. Alpha MSH stimulates melanosome dispersion within dermal melanocytes and melanin biosynthesis within epidermal melanocytes. It also stimulates aldosterone synthesis. Plasma alpha MSH increases in humans with high fever due to endotoxin. Average plasma alpha MSH has been found higher in AIDS patients and also in obese men with insulin resistance.
Aliases
- Pan code
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL plasma collected in a lavender top tube (EDTA)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
Fasting samples are preferred. Patients should be free from medications ( ACTH , Corticosteroids , CNS stimulants ,CNS depressants and blood pressure medications ) for 2 days.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 6 hours
- Frozen: 90 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature or refrigerated
Order Code
AMSTIM
EPIC (Premier) Code
LAB5811
Includes
N/A
CPT Code
- 83520
Billing Code
- 700000
CPT Statement
Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Pan Laboratories, Irvine, CA. This assay has been validated pursuant to the CLIA regulations. It has not been cleared or approved by the U.S. Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Pan Laboratories, LLC
15375 Barranca Pkw
E101
Irvine CA, 92618
15375 Barranca Pkw
E101
Irvine CA, 92618
Reference Range
<100.0 pg/mL
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Friday; Report available: 1 day
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL plasma collected in a lavender top tube (EDTA)
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
Fasting samples are preferred. Patients should be free from medications ( ACTH , Corticosteroids , CNS stimulants ,CNS depressants and blood pressure medications ) for 2 days.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 6 hours
- Frozen: 90 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature or refrigerated
Result Information
Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Extraction
Testing Laboratory
N/A
Reference Range
<100.0 pg/mL
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Friday; Report available: 1 day