PBG Deaminase, Whole Blood
Order Code: PBGD
Test Summary
Confirmation of a diagnosis of acute intermittent porphyria (AIP)
Aliases
- Mayo code PBGD_
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood collected in a sodium heparin green top tube
Minimum Volume
3 mL
Instructions
Refrigerate specimen as soon as possible, 1. Patient’s age is required 2. Include a list of medications the patient is currently taking.
Patient Preparation
Abstinence from alcohol for at least 24 hours prior to specimen collection is essential as ethanol induces porphobilinogen deaminase (PBGD) activity, which may lead to a false-normal result.
Storage
N/A
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature: 7 Days
- Refrigerated: 8 Days
- Frozen: Unacceptable
Limitations
N/A
Other Acceptable Specimens
Lavender top tube (EDTA) or light green top tube (lithium heparin)
Unacceptable Specimens
Gross hemolysis
Order Code
PBGD
EPIC (Premier) Code
LAB6381
Includes
N/A
CPT Code
- 82657
Billing Code
- 650032
CPT Statement
Methodology
Enzymatic End point/Spectrofluorometric
FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905
200 First Street SW
Rochester MN, 55905
Department
Reference Testing
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Tuesday; Report available: 2 - 8 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood collected in a sodium heparin green top tube
Minimum Volume
3 mL
Instructions
Refrigerate specimen as soon as possible, 1. Patient’s age is required 2. Include a list of medications the patient is currently taking.
Patient Preparation
Abstinence from alcohol for at least 24 hours prior to specimen collection is essential as ethanol induces porphobilinogen deaminase (PBGD) activity, which may lead to a false-normal result.
Storage
N/A
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature: 7 Days
- Refrigerated: 8 Days
- Frozen: Unacceptable
Limitations
N/A
Other Acceptable Specimens
Lavender top tube (EDTA) or light green top tube (lithium heparin)
Unacceptable Specimens
Gross hemolysis
Result Information
Methodology
Enzymatic End point/Spectrofluorometric
Testing Laboratory
N/A
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Tuesday; Report available: 2 - 8 days