Myasthenia Gravis Evaluation w/MUSK Reflex, Serum
Test Summary
Diagnosis for autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders Establishing a quantitative baseline value that allows comparison with future levels if weakness is worsening
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL collected in a red top tube
Minimum Volume
2 mL
Instructions
N/A
Patient Preparation
1. Patient should have no general anesthetic or muscle-relaxant drugs in the preceding 24 hours.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room Temperature: 72 hours
- Refrigerated: 28 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis, gross lipemia, gross icterus
Order Code
MGMR
EPIC (Premier) Code
LAB6605
Includes
N/A
CPT Code
- 86041
Billing Code
- 650042
CPT Statement
Methodology
RIA, Flow Cytometry
FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905
200 First Street SW
Rochester MN, 55905
Department
Reference Testing
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Sunday; Reports available: 3 - 10 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL collected in a red top tube
Minimum Volume
2 mL
Instructions
N/A
Patient Preparation
1. Patient should have no general anesthetic or muscle-relaxant drugs in the preceding 24 hours.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
2. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
3. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.
Storage
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room Temperature: 72 hours
- Refrigerated: 28 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis, gross lipemia, gross icterus
Result Information
Methodology
RIA, Flow Cytometry
Testing Laboratory
N/A
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Sunday; Reports available: 3 - 10 days