MET (7Q31), FISH, Tissue
Order Code
M7Q31
Test Summary
Providing prognostic information and guiding treatment primarily for patients with lung, gastric, and renal tumors as well as other tumor types
Aliases
- Mayo code METF
Specimen Collection
Special Instructions
N/A
Preferred Specimen
Submit only 1 of the following specimens:
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Minimum Volume
Slides: 1 Hematoxylin and eosin stained and 2 unstained
Instructions
1. A pathology report is required in order for testing to be performed. Acceptable pathology reports include working drafts, preliminary pathology or surgical pathology reports.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Ambient
Specimen Stability
- N/A
Limitations
N/A
Other Acceptable Specimens
Acceptable: Slides Collection
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Unacceptable Specimens
N/A
Order Code
M7Q31
EPIC (Premier) Code
LAB6446
Includes
N/A
CPT Code
- 88271x2
- 88291 – DNA probe
- each (first probe set)
- Interpretation and report 88271x2 – DNA probe
- each additional probe set (if appropriate) 88271x1 – DNA probe
- each coverage for sets containing 3 probes (if appropriate) 88271x2 – DNA probe
- each coverage for sets containing 4 probes (if appropriate) 88271x3 – DNA probe
- each coverage for sets containing 5 probes (if appropriate) 88274 w/modifier 52 – Interphase in situ hybridization
- < 25 cells
- each probe set (if appropriate) 88274 – Interphase in situ hybridization 25 to 99 cells
- each probe set (if appropriate) 88275 – Interphase in situ hybridization 100 to 300 cells
- each probe set (if appropriate)
Billing Code
- 671185
- 671186
CPT Statement
Methodology
Fluorescence In Situ Hybridization (FISH)
FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905
200 First Street SW
Rochester MN, 55905
Department
Reference Testing
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 7 - 10 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
Submit only 1 of the following specimens:
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Specimen Type: Tissue
Preferred: Tissue block Collection Instructions: Submit a formalin-fixed, paraffin-embedded (FFPE) tumor tissue block.
Blocks prepared with alternative fixation methods may be acceptable; provide fixation method used.
Minimum Volume
Slides: 1 Hematoxylin and eosin stained and 2 unstained
Instructions
1. A pathology report is required in order for testing to be performed. Acceptable pathology reports include working drafts, preliminary pathology or surgical pathology reports.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Ambient
Specimen Stability
- N/A
Limitations
N/A
Other Acceptable Specimens
Acceptable: Slides Collection
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Instructions: Four consecutive, unstained, 5 micron-thick sections placed on positively charged slides, and 1 hematoxylin and eosin-stained slide.
Unacceptable Specimens
N/A
Billing
CPT Code
- 88271x2
- 88291 – DNA probe
- each (first probe set)
- Interpretation and report 88271x2 – DNA probe
- each additional probe set (if appropriate) 88271x1 – DNA probe
- each coverage for sets containing 3 probes (if appropriate) 88271x2 – DNA probe
- each coverage for sets containing 4 probes (if appropriate) 88271x3 – DNA probe
- each coverage for sets containing 5 probes (if appropriate) 88274 w/modifier 52 – Interphase in situ hybridization
- < 25 cells
- each probe set (if appropriate) 88274 – Interphase in situ hybridization 25 to 99 cells
- each probe set (if appropriate) 88275 – Interphase in situ hybridization 100 to 300 cells
- each probe set (if appropriate)
Billing Code
- 671185
- 671186
CPT Statement
Result Information
Methodology
Fluorescence In Situ Hybridization (FISH)
Testing Laboratory
N/A
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 7 - 10 days