Dementia Autoimmune Evaluation, CSF
Order Code: DMC2
Test Summary
Investigating new onset dementia and cognitive impairment plus 1 or more of the following accompaniments using cerebrospinal fluid specimens: -Rapid onset and progression -Fluctuating course -Psychiatric accompaniments (psychosis, hallucinations) -Movement disorder (myoclonus, tremor, dyskinesias) -Headache -Autoimmune stigmata (personal history or family history or signs of diabetes mellitus, thyroid disorder, vitiligo, poliosis [premature graying], myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus) -Smoking history (20+ pack years) or other cancer risk factors -History of cancer -Inflammatory cerebrospinal fluid -Neuroimaging findings atypical for degenerative etiology.
Aliases
- Mayo code DMC2
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL CSF in collection vial number 1
Minimum Volume
2 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Sterile Vial
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature: 72 hours
- Refrigerated: 28 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Any CSF collection vial
Unacceptable Specimens
- Gross hemolysis
- Gross lipemia
- Gross icterus
Order Code
DMC2
EPIC (Premier) Code
LAB6440
Includes
N/A
CPT Code
- 86341
- 86255 (x23)
Billing Code
- 650007
- 650008
CPT Statement
Methodology
Indirect Immunofluorescence Assay (IFA),
Cell-Binding Assay (CBA),
Western Blot (WB),
Immunoblot (IB),
Radioimmunoassay (RIA)
Cell-Binding Assay (CBA),
Western Blot (WB),
Immunoblot (IB),
Radioimmunoassay (RIA)
FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905
200 First Street SW
Rochester MN, 55905
Department
Reference Testing
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Sunday; Report available: 8 -12 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL CSF in collection vial number 1
Minimum Volume
2 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Sterile Vial
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature: 72 hours
- Refrigerated: 28 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Any CSF collection vial
Unacceptable Specimens
- Gross hemolysis
- Gross lipemia
- Gross icterus
Result Information
Methodology
Indirect Immunofluorescence Assay (IFA),
Cell-Binding Assay (CBA),
Western Blot (WB),
Immunoblot (IB),
Radioimmunoassay (RIA)
Cell-Binding Assay (CBA),
Western Blot (WB),
Immunoblot (IB),
Radioimmunoassay (RIA)
Testing Laboratory
N/A
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Monday - Sunday; Report available: 8 -12 days