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Test Directory

Test Directory CNS, Demyelinating Disease Eval, Serum

CNS, Demyelinating Disease Eval, Serum

Test Summary

Diagnosis of inflammatory demyelinating diseases (IDDs) with similar phenotype to neuromyelitis optica spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis

Diagnosis of autoimmune myelin oligodendrocyte glycoprotein (MOG)-opathy

Diagnosis of neuromyelitis optica (NMO) Distinguishing NMOSD, acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis from multiple sclerosis early in the course of disease

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL serum collected in a red top tube

Minimum Volume

2 mL

Instructions

N/A

Patient Preparation

For optimal antibody detection, specimen collection is recommended before initiation of immunosuppressant medication.

Storage

Plastic screw-cap vial

Transport Temperature

Refrigerated

Specimen Stability

Room Temperature: 72 Hours
Refrigerated: 28 Days
Frozen: 28 Days

Limitations

N/A

Other Acceptable Specimens

Serum from a serum separator tube

Unacceptable Specimens

Gross hemolysis, gross lipemia, gross icterus

Order Code

CNSDD

EPIC (Premier) Code

LAB6438

Includes

N/A

CPT Code

86053
86363
86053-Titer (if appropriate 86363-Titer (if appropriate)iate)

Billing Code

671155, 671156

CPT Statement

Methodology

Flow Cytometry (FC)

FDA Status

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905

Department

Reference Testing

Reference Range

N/A

Setup Schedule / Expected Turnaround Time

Monday, Tuesday, Thursday; Report available: 7 - 10 days