Apolipoprotein E Genotyping, B
Order Code:
APOEG
Test Summary
Determining the specific apolipoprotein E (APOE) genotypes in individuals with type III hyperlipoproteinemia. Determining the specific apolipoprotein E (APOE) genotypes that may increase risk for amyloid related imaging abnormalities in individuals being treated for Alzheimer disease with B-amyloid-targeting antibodies. APOE genotyping has been used to assess susceptibility for Alzheimer disease. However, the use of APOE analysis for predictive testing for Alzheimer disease is not currently recommended by the American College of Medical Genetics due to limited clinical utility and poor predictive value.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL whole blood collected in an EDTA lavender top tube
Minimum Volume
1 mL
Instructions
Collect whole blood in an EDTA lavender top tube. Invert several times to mix. Do no aliquot.
Patient Preparation
A previous bone marrow transplant from an allogenic donor will interfere with testing. Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant.
Storage
N/A
Transport Temperature
N/A
Specimen Stability
- N/A
Limitations
N/A
Other Acceptable Specimens
Whole blood collected in an ACD yellow top tube
Unacceptable Specimens
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Order Code
APOEG
EPIC (Premier) Code
LAB6771
Includes
N/A
CPT Code
- 81401
Billing Code
- 671278
CPT Statement
Methodology
Polymerase Chain Reaction (PCR) including Restriction Digest
FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester MN, 55905
200 First Street SW
Rochester MN, 55905
Department
Reference Testing
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Report available: 6 - 7 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL whole blood collected in an EDTA lavender top tube
Minimum Volume
1 mL
Instructions
Collect whole blood in an EDTA lavender top tube. Invert several times to mix. Do no aliquot.
Patient Preparation
A previous bone marrow transplant from an allogenic donor will interfere with testing. Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant.
Storage
N/A
Transport Temperature
N/A
Specimen Stability
- N/A
Limitations
N/A
Other Acceptable Specimens
Whole blood collected in an ACD yellow top tube
Unacceptable Specimens
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Result Information
Methodology
Polymerase Chain Reaction (PCR) including Restriction Digest
Testing Laboratory
N/A
Reference Range
N/A
Setup Schedule / Expected Turnaround Time
Report available: 6 - 7 days