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Total Glutathione

Test Summary

Glutathione is a tripeptide formed by a peptide linkage between the amine group of cysteine linked to glycine and the carboxyl group of the glutamate side-chain. It is an abundant cellular reducing agent, whose major biological function is mitigating oxidative damage to biological macromolecules. Glutathione is also important in the metabolism and excretion of xenobiotic compounds. Glutathione is consumed to maintain cells in a reduced condition. Consequently, glutathione levels in patient samples are expected to be diminished in disease states where oxygen reactive species are involved, such as rheumatoid arthritis and atherosclerosis. Low glutathione levels have been linked to reduced dopamine production in neurons, which suggests a relationship to dopamine based neurological disorders such as Parkinson’s disease. High levels of glutathione have been linked to chemotherapy resistance in cancer treatments.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

10 mL whole blood collected in ACD Solution A or B tube

Minimum Volume

Solution A: 8.5mL draw;
Solution B: 6mL draw

Instructions

Ship refrigerated on ice packs. Do not place specimens directly on ice packs

Patient Preparation

N/A

Storage

ACD A or B Tube

Transport Temperature

Refrigerated

Specimen Stability

  • Room Temperature: Unacceptable
  • Refrigerated: 21 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Specimens received room temperature or frozen. Hemolyzed specimens. Samples oversaturated with ACD solution

Order Code

TLGLUT

EPIC (Premier) Code

LAB6033

Includes

N/A

CPT Code

  • 82978

Billing Code

  • 600000

CPT Statement

CPT Statement

Methodology

Kinetic

FDA Status

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

BioAgilytix Diagnostics
1320 Soldiers Field Rd
Boston MA, 2135

Reference Range

373-838 µM

Setup Schedule / Expected Turnaround Time

Report available: Up to 3 business days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

10 mL whole blood collected in ACD Solution A or B tube

Minimum Volume

Solution A: 8.5mL draw;
Solution B: 6mL draw

Instructions

Ship refrigerated on ice packs. Do not place specimens directly on ice packs

Patient Preparation

N/A

Storage

ACD A or B Tube

Transport Temperature

Refrigerated

Specimen Stability

  • Room Temperature: Unacceptable
  • Refrigerated: 21 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Specimens received room temperature or frozen. Hemolyzed specimens. Samples oversaturated with ACD solution

Billing

CPT Code

  • 82978

Billing Code

  • 600000

CPT Statement

CPT Statement

Result Information

Methodology

Kinetic

Testing Laboratory

N/A

Reference Range

373-838 µM

Setup Schedule / Expected Turnaround Time

Report available: Up to 3 business days