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Test Directory

Histoplasma AG, Serum, EIA

Test Summary

Histoplasma capsulatum is a pathogenic dimorphic fungus of worldwide distribution which is endemic to the Ohio and Mississippi River valleys in the United States and to certain regions of Central and South America. The definitive diagnosis of Histoplasmosis is the isolation of H. capsulatum by culture from clinical specimens. However, cultures usually take 2 to 4 weeks before identification of fungus is possible. Serological methods offer a rapid alternative to microbiological techniques using immunodiffusion or complement fixation. Unfortunately, anti-H. capsulatum antibody titers remain elevated months or even years after successful therapy, and as a result it may not be possible to differentiate between subacute or inactive infections, chronic active forms, and relapses (frequently seen among AIDS patients). This assay detects the presence of H. capsulatum antigen in body fluids.

Aliases

  • N/A

Specimen Collection

Special Instructions

Pap results requiring physician interpretation will be performed at an additional charge (CPT code(s): 88141). For Interpretations of Atypical Squamous Cells (ASC), a test for HPVHR will be performed at an additional charge (CPT code(s): 87624).

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

:SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the tube for at least 10 minutes. Keep tightly stoppered

Patient Preparation

N/A

Storage

SST (speckled top), Red top, Plastic Vial (transfer) tube

Transport Temperature

Refrigerated

Specimen Stability

  • Room Temperature: N/A
  • Refrigerated: 3 DAYS
  • Frozen: UNACCEPTABLE

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Rejected if stored at room temperature. Frozen specimen.

Order Code

HSTAGS

EPIC (Premier) Code

LAB6744

Includes

N/A

CPT Code

  • 87385

Billing Code

  • 500234

CPT Statement

Methodology

Enzyme Immunoassay (EIA)

FDA Status

No - This test was developed, and its performance characteristics determined by CompuNet Clinical Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439

Department

Molecular/Serology

Reference Range

SEX     AGE      Report Normals      Units
N/M/F 1000Y      <2.0 = Negative     EIA Units
                    2.0 - 2.9 = intermediate EIA Units
                     > or = to 3.0 = Positive EIA Units

Setup Schedule / Expected Turnaround Time

Monday - Friday; BS; Report available 1 - 3 days

Specimen Collection

Special Instructions

Pap results requiring physician interpretation will be performed at an additional charge (CPT code(s): 88141). For Interpretations of Atypical Squamous Cells (ASC), a test for HPVHR will be performed at an additional charge (CPT code(s): 87624).

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

:SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the tube for at least 10 minutes. Keep tightly stoppered

Patient Preparation

N/A

Storage

SST (speckled top), Red top, Plastic Vial (transfer) tube

Transport Temperature

Refrigerated

Specimen Stability

  • Room Temperature: N/A
  • Refrigerated: 3 DAYS
  • Frozen: UNACCEPTABLE

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Rejected if stored at room temperature. Frozen specimen.

Billing

CPT Code

  • 87385

Billing Code

  • 500234

CPT Statement

Result Information

Methodology

Enzyme Immunoassay (EIA)

Testing Laboratory

N/A

Reference Range

SEX     AGE      Report Normals      Units
N/M/F 1000Y      <2.0 = Negative     EIA Units
                    2.0 - 2.9 = intermediate EIA Units
                     > or = to 3.0 = Positive EIA Units

Setup Schedule / Expected Turnaround Time

Monday - Friday; BS; Report available 1 - 3 days