Beta Glycoprotein
Order Code:
B2GMA
Test Summary
Anti-phospholipid antibodies are a heterogeneous group of immunoglobulins that bind to several anionic phospholipids, including cardiolipin and phosphatidylserine. High serum levels of anti-phospholipid antibodies are frequently detected in patients with autoimmune (e.g., SLE) and non-autoimmune diseases, as well as in apparently healthy individuals. These antibodies have been associated with an increased risk for recurrent arterial and venous thrombotic events, thrombocytopenia, and fetal loss. These manifestations are the main features of the anti-phospholipid syndrome (APS).
Aliases
- Beta 2 Glycoprotein 1
- B2GP (IgG/IgM/IgA)
- B2GP1 (IgG/IgM/IgA)
Specimen Collection
Special Instructions
See Link and Print "Drug List for Special Coagualtion Tests"
Preferred Specimen
1 SST (speckled top) or 2 GST (gold top) tube(s)
Minimum Volume
2 Frozen Capped aliquots of at least 0.5 mL serum (Polypropylene tubes recommended)
Instructions
Use standard venipuncture and disposal techniques.
SST/GST tube: Avoid hemolysis.
1. Invert a minimum of 5 times, and then allow clotting in an upright position for 30 minutes.
2. Centrifuge the SST/GST for at 3000 rpm for 10 minutes.
3. Spun SST/GST tube remains at refrigerated temperature (2-8 degrees C) for transport up to 72 hours.
4. Serum must be removed from original SST/GST tube and frozen at <-20 degrees C in plastic polypropylene aliquot tubes within 72 hours of collection. Refer to the Minimum Volume section above for the number of aliquots required per test.
SST/GST tube: Avoid hemolysis.
1. Invert a minimum of 5 times, and then allow clotting in an upright position for 30 minutes.
2. Centrifuge the SST/GST for at 3000 rpm for 10 minutes.
3. Spun SST/GST tube remains at refrigerated temperature (2-8 degrees C) for transport up to 72 hours.
4. Serum must be removed from original SST/GST tube and frozen at <-20 degrees C in plastic polypropylene aliquot tubes within 72 hours of collection. Refer to the Minimum Volume section above for the number of aliquots required per test.
Patient Preparation
N/A
Storage
SST (speckled top) tube or GST (gold top) tube
OR
Frozen- Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
OR
Frozen- Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Transport Temperature
Room Temperature: Unacceptable
Refrigerated: SST (speckled top) tube or GST (gold top) tube
Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Refrigerated: SST (speckled top) tube or GST (gold top) tube
Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Specimen Stability
- Room Temperature: Unacceptable
- Refrigerated: SST (speckled top) or GST (gold top) tube <
- 72 hours
- Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended) at <
- -20⁰C for <
- 60 days
- at <
- -70⁰C for 12months
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis, lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample
Order Code
B2GMA
EPIC (Premier) Code
LAB474
Includes
Beta 2 GP1 IgA
Beta 2 GP1 IgG
Beta 2 GP1 IgM
Beta 2 GP1 IgG
Beta 2 GP1 IgM
CPT Code
- 86146(3)
Billing Code
- 300510
CPT Statement
Methodology
ELISA
FDA Status
FDA approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439
2308 Sandridge Drive
Moraine OH, 45439
Department
Hematology
Reference Range
See Report
Setup Schedule / Expected Turnaround Time
Monday, Thursday; SCOAG; Report available: 1 - 4 days
Specimen Collection
Special Instructions
See Link and Print "Drug List for Special Coagualtion Tests"
Preferred Specimen
1 SST (speckled top) or 2 GST (gold top) tube(s)
Minimum Volume
2 Frozen Capped aliquots of at least 0.5 mL serum (Polypropylene tubes recommended)
Instructions
Use standard venipuncture and disposal techniques.
SST/GST tube: Avoid hemolysis.
1. Invert a minimum of 5 times, and then allow clotting in an upright position for 30 minutes.
2. Centrifuge the SST/GST for at 3000 rpm for 10 minutes.
3. Spun SST/GST tube remains at refrigerated temperature (2-8 degrees C) for transport up to 72 hours.
4. Serum must be removed from original SST/GST tube and frozen at <-20 degrees C in plastic polypropylene aliquot tubes within 72 hours of collection. Refer to the Minimum Volume section above for the number of aliquots required per test.
SST/GST tube: Avoid hemolysis.
1. Invert a minimum of 5 times, and then allow clotting in an upright position for 30 minutes.
2. Centrifuge the SST/GST for at 3000 rpm for 10 minutes.
3. Spun SST/GST tube remains at refrigerated temperature (2-8 degrees C) for transport up to 72 hours.
4. Serum must be removed from original SST/GST tube and frozen at <-20 degrees C in plastic polypropylene aliquot tubes within 72 hours of collection. Refer to the Minimum Volume section above for the number of aliquots required per test.
Patient Preparation
N/A
Storage
SST (speckled top) tube or GST (gold top) tube
OR
Frozen- Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
OR
Frozen- Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Transport Temperature
Room Temperature: Unacceptable
Refrigerated: SST (speckled top) tube or GST (gold top) tube
Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Refrigerated: SST (speckled top) tube or GST (gold top) tube
Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended)
Specimen Stability
- Room Temperature: Unacceptable
- Refrigerated: SST (speckled top) or GST (gold top) tube <
- 72 hours
- Frozen: Capped aliquots of at least 0.5 mL serum (polypropylene tubes recommended) at <
- -20⁰C for <
- 60 days
- at <
- -70⁰C for 12months
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis, lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample
Result Information
Methodology
ELISA
Testing Laboratory
N/A
Reference Range
See Report
Setup Schedule / Expected Turnaround Time
Monday, Thursday; SCOAG; Report available: 1 - 4 days