Alpha 1 Antitrypsin
Test Summary
Alpha-1-Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia.
Aliases
- ALPHA 1-Protease Inhibitor
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1mL serum
Minimum Volume
0.5 mL serum
Instructions
Barrier tubes (serum separator tubes) are preferred. If non-barrier tubes are utilized, the serum must be removed immediately after centrifuging and placed in a screw-cap transfer tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Patient Preparation
N/A
Storage
Original tube preferred, may be sent in a screw-top transfer tube.
Transport Temperature
Room temperature
Specimen Stability
- Room Temperature: 24 hours
- Refrigerated: 7 days
- Frozen: at least 7 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, contaminated sample.
Order Code
A1AT
EPIC (Premier) Code
LAB026
Includes
N/A
CPT Code
- 82103
Billing Code
- 300000
CPT Statement
Methodology
Immunoturbidimetric Assay
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439
2308 Sandridge Drive
Moraine OH, 45439
Reference Range
Normal adult serum: 90 – 200 mg/dL
Setup Schedule / Expected Turnaround Time
Monday, Thursday; BS; Report available: 1 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1mL serum
Minimum Volume
0.5 mL serum
Instructions
Barrier tubes (serum separator tubes) are preferred. If non-barrier tubes are utilized, the serum must be removed immediately after centrifuging and placed in a screw-cap transfer tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Patient Preparation
N/A
Storage
Original tube preferred, may be sent in a screw-top transfer tube.
Transport Temperature
Room temperature
Specimen Stability
- Room Temperature: 24 hours
- Refrigerated: 7 days
- Frozen: at least 7 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, contaminated sample.
Result Information
Methodology
Immunoturbidimetric Assay
Testing Laboratory
N/A
Reference Range
Normal adult serum: 90 – 200 mg/dL
Setup Schedule / Expected Turnaround Time
Monday, Thursday; BS; Report available: 1 - 5 days