Catecholamines, Fract with Creatinine, 24 Hr Urine
Order Code:
24CATC
Test Summary
The three catecholamines (norepinephrine, epinephrine and dopamine) are the principal secretory products of neural tissue. Clinically, the measurement of circulating catecholamines is valuable in the diagnosis of catecholamine secreting tumors associated chiefly with hypertension (pheochromocytomas, neuroblastomas and gangliomas) and with the evaluation of orthostatic hypotension.
Aliases
- Catecholamines
- Free
- Dopamine
- Epinephrine
- Adrenaline
- Norepinephrine
- Noradrenaline
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL preserved 24-hour urine with 25 mL 6N HCl collected in a plastic 24-hour urine container
Minimum Volume
0.7 mL
Instructions
Collect 24-hour urine with 25 mL 6N HCL to maintain a pH < or = 3. If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Preserved urine
- Room Temp: Unacceptable
- Refrig: 30 Days
- Frozen: 60 Days
- Unpreserved urine
- Room temperature: Unacceptable
- Refrigerated: 7 days
- Frozen: 60 days
Limitations
N/A
Other Acceptable Specimens
If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Unacceptable Specimens
Preserved urine received refrigerated with pH >3 Unpreserved urine received frozen with pH >6
Order Code
24CATC
EPIC (Premier) Code
LAB3956
Includes
Epinephrine, Norepinephrine, Calculated Total (E+NE), Dopamine, and Creatinine
CPT Code
- 82384
- 82570
Billing Code
- 671362
- 671363
CPT Statement
Methodology
Liquid Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 3 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL preserved 24-hour urine with 25 mL 6N HCl collected in a plastic 24-hour urine container
Minimum Volume
0.7 mL
Instructions
Collect 24-hour urine with 25 mL 6N HCL to maintain a pH < or = 3. If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Patient Preparation
It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Preserved urine
- Room Temp: Unacceptable
- Refrig: 30 Days
- Frozen: 60 Days
- Unpreserved urine
- Room temperature: Unacceptable
- Refrigerated: 7 days
- Frozen: 60 days
Limitations
N/A
Other Acceptable Specimens
If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Unacceptable Specimens
Preserved urine received refrigerated with pH >3 Unpreserved urine received frozen with pH >6
Result Information
Methodology
Liquid Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 3 - 4 days