Test Summary

Used to screen pregnant women for obstetric cholestasis. Symptoms of cholestasis included persistent itching in the third trimester of pregnancy and possible risks of unborn baby including stillbirth, premature labor and bleeding. The frequency of obstetric cholestasis varies and is 1 in 100 in pregnant European women vs. 1 in 10 in South American women. Total bile acids levels are the most sensitive indicator for monitoring the effectiveness of interferon treatment of chronic hepatitis C patients. Total bile acids are metabolized in the liver and, hence, serve as a marker for normal liver function. Serum total bile acids are increased in patients with acute hepatitis, chronic hepatitis, liver sclerosis and liver cancer.

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