Myleoproliferative Neoplasma Core DX Panel
NGSMPN
Test Summary
Myeloproliferative Neoplasm is an NGS based assay, which targets driver mutations in JAK2 (exon 14; V617F and exon12), CALR (exon 9, a 52-bp deletion, type 1 and a 5-bp insertion, type 2 mutation) are the most frequent variants.), and MPL (exon 10), as part of the early evaluation for BCR-ABL1-negative myeloproliferative neoplasms (MPN's), including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF).
Aliases
N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood in lavender top (EDTA)
Minimum Volume
1 mL whole bloodÂ
Instructions
- Collect and label sample according to standard protocols.
- Gently invert tube 5 times immediately after draw. DO NOT SHAKE!
- Store and transport room temperature.
Patient Preparation
N/A
Storage
Refrigerated
Transport Temperature
Room Temperature
Specimen Stability
- Room temprature: 24 hrs
- Refrigerated: 3-5 days
Limitations
Variants outside the targeted regions or below the limit of detection will not be identified.
Other Acceptable Specimens
- 4mL whole blood in green top (sodium heparin) tube
Unacceptable Specimens
DO NOT FREEZE. Specimen viability decreases during transportation. Sent to Lab for viability determination.
Order Code
NGSMPN
EPIC (Premier) Code
- LAB6884
Includes
JAK2, MPL, CALR genes
CPT Code
- 81270
- 81339
- 81219
- 81279
Billing Code
- 300106
- 300108
- 300109
- 300122
CPT Statement
Methodology
Next Generation Sequencing
FDA Status
Not FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
2308 Sandridge Drive
Moraine OH, 45439
Department
Reference Range
Low limit of detection is 5%
Setup Schedule / Expected Turnaround Time
Report available: 5-7 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood in lavender top (EDTA)
Minimum Volume
1 mL whole bloodÂ
Instructions
- Collect and label sample according to standard protocols.
- Gently invert tube 5 times immediately after draw. DO NOT SHAKE!
- Store and transport room temperature.
Patient Preparation
N/A
Storage
Refrigerated
Transport Temperature
Room Temperature
Specimen Stability
- Room temprature: 24 hrs
- Refrigerated: 3-5 days
Limitations
Variants outside the targeted regions or below the limit of detection will not be identified.
Other Acceptable Specimens
- 4mL whole blood in green top (sodium heparin) tube
Unacceptable Specimens
DO NOT FREEZE. Specimen viability decreases during transportation. Sent to Lab for viability determination.
Billing
CPT Code
- 81270
- 81339
- 81219
- 81279
Billing Code
- 300106
- 300108
- 300109
- 300122
CPT Statement
Result Information
Methodology
Next Generation Sequencing
Testing Laboratory
Reference Range
Low limit of detection is 5%
Setup Schedule / Expected Turnaround Time
Report available: 5-7 days