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Voriconazole, Serum

Test Summary

N/A

Aliases

Vfend (Voriconazole)

Specimen Collection

Special Instructions

Trough level (ie, immediately before next dose) monitoring is recommended.

Preferred Specimen

2 mL serum from a red top tube

Minimum Volume

0.6 mL

Instructions

Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Patient Preparation

N/A

Storage

Refrigerated

Transport Temperature

Refrigerated

Specimen Stability

  • Room temperature: 28 days
  • Refrigerated: 28 days
  • Frozen: 28 days

Limitations

Voriconazole metabolism may be altered by coadministration of drugs that metabolically induce or inhibit cytochrome P450 2C19 or by genetic alterations that affect enzyme activity.

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum from a SST

Order Code

N/A

EPIC (Premier) Code

N/A

Includes

Voriconazole level

CPT Code

80285

Billing Code

N/A

CPT Statement

CPT Statement

Methodology

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

FDA Status

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Mayo Clinic Laboratories -- Rochester Superior Drive
3050 Superior Drive NW
Rochester MN, 55901

Department

N/A

Reference Range

1.0-5.5 mcg/mL

Setup Schedule / Expected Turnaround Time

1-2 Days, Monday-Sunday

Specimen Collection

Special Instructions

Trough level (ie, immediately before next dose) monitoring is recommended.

Preferred Specimen

2 mL serum from a red top tube

Minimum Volume

0.6 mL

Instructions

Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Patient Preparation

N/A

Storage

Refrigerated

Transport Temperature

Refrigerated

Specimen Stability

  • Room temperature: 28 days
  • Refrigerated: 28 days
  • Frozen: 28 days

Limitations

Voriconazole metabolism may be altered by coadministration of drugs that metabolically induce or inhibit cytochrome P450 2C19 or by genetic alterations that affect enzyme activity.

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum from a SST

Billing

CPT Code

80285

Billing Code

N/A

CPT Statement

CPT Statement

Result Information

Methodology

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Testing Laboratory

N/A

Reference Range

1.0-5.5 mcg/mL

Setup Schedule / Expected Turnaround Time

1-2 Days, Monday-Sunday