AD Detect ® Phosphorylated TAU181 (P-TAU181)
Test Summary
Quest AD-Detect® Phosphorylated tau181(p-tau181), Plasma - p-tau181 is a diagnostic biomarker for Alzheimer's Disease (AD) that is useful in identifying patients with underlying AD tau pathology. It can predict the cognitive decline in AD/MCI patients and correlates with amyloid and tau PET results.
Aliases
- PhosphoTau-181P
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in an EDTA (lavender-top) tube. Room Temperature
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
Room Temperature
Transport Temperature
Room Temperature
Specimen Stability
- Room Temperature: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis
Order Code
ADP181
EPIC (Premier) Code
LAB6916
Includes
N/A
CPT Code
- 84398
Billing Code
- 670162
CPT Statement
Methodology
Electrochemiluminescence (ECLIA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Reference Range
- <55 years ≤0.86 pg/mL
- ≥55 years ≤1.07 pg/Ml
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 1 - 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in an EDTA (lavender-top) tube. Room Temperature
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Storage
Room Temperature
Transport Temperature
Room Temperature
Specimen Stability
- Room Temperature: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis
Result Information
Methodology
Electrochemiluminescence (ECLIA)
Testing Laboratory
N/A
Reference Range
- <55 years ≤0.86 pg/mL
- ≥55 years ≤1.07 pg/Ml
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 1 - 3 days