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Valproic Acid (Depakene)

Test Summary

Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches, and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites can increase the concentration of Valproic Acid.

Aliases

  • Depakene
  • Depakote
  • Depakote VPA
  • Valproate
  • VPA

Specimen Collection

Special Instructions

N/A

Preferred Specimen

N/A

Minimum Volume

1 mL

Instructions

Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube.

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room Temperature = 2 days
  • Refrigerated = 7 days
  • Frozen = 3 months

Limitations

N/A

Other Acceptable Specimens

Plasma from Lithium Heparin (Light Green Top) tube

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.

Order Code

VALP

EPIC (Premier) Code

LAB408

Includes

N/A

CPT Code

  • 80164

Billing Code

  • 301045

CPT Statement

Methodology

Immunoassay (IA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439

Department

Chemistry

Reference Range

50-100 mcg/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily

Specimen Collection

Special Instructions

N/A

Preferred Specimen

N/A

Minimum Volume

1 mL

Instructions

Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube.

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room Temperature = 2 days
  • Refrigerated = 7 days
  • Frozen = 3 months

Limitations

N/A

Other Acceptable Specimens

Plasma from Lithium Heparin (Light Green Top) tube

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.

Billing

CPT Code

  • 80164

Billing Code

  • 301045

CPT Statement

Result Information

Methodology

Immunoassay (IA)

Testing Laboratory

N/A

Reference Range

50-100 mcg/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily